The Columbia High School Hall of Fame is a program which recognizes and applauds the work of CHS graduates who have a positive and profound impact on society through personal achievement, scholarly pursuit, or community service. To be nominated, a candidate must have graduated from Columbia High School and have demonstrated achievement in their profession or in an area in which they take an active interest, or have shown outstanding service to a specific community including those outside East Greenbush, or have contributed to or served humanity in some special way. The names of the Hall of Fame members are inscribed on a plaque that is prominently displayed in Columbia High School for all to admire.

Following the 2007 induction ceremony, the Hall of Fame membership numbered 49, the earliest graduate being from the year 1941 and the most recent from the class of 1998.